The peak you track
Import Bruker or CSV, identify gradient ramps and select local maxima from original data. Lines and panels display D and Rh for each resonance.
DiffAtOnce / LegacyDiffAtOnce
THE ORIGINAL IDEA, RENEWED
DiffAtOnce
Legacy.
The classic DiffAtOnce workflow, centred on the spectrum. Select, track, fit and interpret your resonances in a renewed workspace.
The spirit of 2013.
A renewed way to work.
FROM SPECTRUM TO REPORT
Every step visible. Every decision reviewable.
A considered attenuation fit
Review the fit and noise tail. Include or exclude points and retain decisions for each resonance and ramp.
Size and shape
Apply temperature and internal-reference corrections, estimate Rh and compare sphere, cylinder, ellipsoid and microfriction models. Shape requires additional evidence.
Mass and reports
Explore apparent molecular mass at high dilution or with concentration. Export PDF, PostScript, EPS, Excel and CSV with conditions, equations and provenance.
YOUR WORKSPACE
Light or dark.
The same rigour.
Switch themes in the sidebar. Your preference is remembered; spectra and results retain their values. Spanish and English help is built in and works offline.
Download, register and begin.
- Download the ZIP and extract the entire folder on Windows x64. No separate .NET installation is required.
- Open DiffAtOnce.exe. Read the registration notice and request access for your installation.
- The owner manages approval at diffatonce.com. Once approved, check access and continue.
Identity corresponds to the product, installation folder and Windows user. Keeping the same folder helps preserve identity during updates.
DiffAtOnce Legacy 2.6.1 · Windows x64 ↓63.6 MiB · SHA-256
cbfe18fb6a8d13243edbab7cca5e540ed5d2f9861daf1f68bd7507ccb53fd261Remote access control uses the same protocol as Prime and ResinAtOnce. It checks at startup and every 15 minutes; offline use is limited by the last signed authorization, 24 hours by default. Blocking never deletes projects.
No protection mechanism is invulnerable to modified clients. Older versions do not include this control.
Legacy support →DIFFATONCE / MOLECULAR DIFFUSION